
Truffel microdoseringen (FP)
Microdosering
van Cibdol
Cibdol Truffle Microdoses (FP) — The Gentle Introduction to Psilocybin Microdosing
Cibdol Truffle Microdoses (FP) contain six pre-portioned 1 g doses of Psilocybe mexicana sclerotia, designed for the Fadiman Protocol — the most conservative microdosing schedule available. One day on, two days off. This is the product we hand to anyone who walks into Azarius and says "I want to try microdosing but I've never touched psilocybin before." The FP is built for that exact moment: low intensity, maximum rest days, and the mildest truffle species in the Cibdol line.
Psilocybe mexicana is the gentlest of the three species Cibdol uses across their microdosing range. Where P. tampanensis (OP) leans toward analytical sharpness and P. galindoi (SP) targets creative flow, mexicana's character profile centres on relaxation, emotional integration, and inner calm. At 1 g fresh — roughly 0.3 g dry, containing approximately 1-2 mg of psilocybin — you are well below the perceptual threshold. No visuals, no body load, no impairment. What users consistently report is a quiet reduction in background stress, a greater ease in processing emotions, and a gentler baseline mood across the dosing cycle.
The "FP" stands for Fadiman Protocol, named after psychologist James Fadiman, who popularised the 1-on-2-off schedule in the early 2010s. Fadiman's reasoning was straightforward: dose on Day 1, observe aftereffects on Day 2, return to baseline on Day 3, then repeat. The two rest days make it the most forgiving protocol — if you're sensitive to psilocybin, you have ample time to recalibrate. We've sold all three Cibdol protocols since launch, and the FP outsells the other two among first-time buyers by a clear margin. People start here, figure out how their body responds, then decide whether to move to the SP or OP later.
Dosage Guide — Truffle Microdoses (FP)
Each dose is 1 g of fresh Psilocybe mexicana sclerotia. Fresh truffles contain 65-70% water, so 1 g fresh yields roughly 0.3 g dry weight — equivalent to approximately 1-2 mg of psilocybin. That is sub-perceptual: no visuals, no altered state, no impairment.
- Timing: Take your dose in the morning, on an empty stomach. Psilocybin is a prodrug — your liver converts it to psilocin via dephosphorylation, and absorption is fastest without food competing for metabolic bandwidth.
- Method: Chew the truffle thoroughly before swallowing. Breaking down the sclerotia tissue in your mouth speeds up onset. Wash it down with water or juice if you prefer.
- Schedule: Day 1 — dose. Day 2 — observe (no dose, but note how you feel). Day 3 — baseline (back to normal). Day 4 — dose again. Repeat. This gives you 2-3 active days per week.
- Duration: One pack of 6 doses lasts roughly 18 days on the Fadiman schedule. Most protocols recommend cycling for 4-8 weeks, then taking a 2-4 week break to prevent tolerance and assess your baseline.
- Journaling: Track your mood, stress levels, emotional responses, and sleep quality on dose days, observation days, and rest days. The Fadiman Protocol's three-day rhythm was specifically designed for this kind of self-observation — Day 2 is where you notice the afterglow, Day 3 is where you see what's changed without the compound.
Microdose (this product): 1 g fresh / ~0.3 g dry / ~1-2 mg psilocybin. No perceptual effects. Emotional and mood support only.
If you've done a full cycle on the FP and want something with more active days per week, try the Stamets Protocol (SP) — it uses a medium-potency species on a 4-5-on, 2-3-off schedule.
Specifications — Truffle Microdoses (FP)
| Species | Psilocybe mexicana (sclerotia) |
| Active compounds | Psilocybin (prodrug), psilocin (active metabolite, serotonergic 5-HT2A receptor agonist), baeocystine (minor tryptamine alkaloid) |
| Dose per portion | 1 g fresh sclerotia (~0.3 g dry, ~1-2 mg psilocybin) |
| Portions per pack | 6 |
| Protocol | Fadiman Protocol — 1 day on, 2 days off |
| Active days per week | 2-3 |
| Character | Relaxation, emotional integration, inner calm, stability |
| Perceptual level | Sub-perceptual — no visuals, no altered state |
| Brand | Cibdol |
| Storage | Refrigerate at 2-8 °C. Perishable — use within the shelf date on packaging. |
Ready for more? Pair with the other Cibdol protocols
Once you've completed a full Fadiman cycle and know how your body responds, consider stepping up. The Truffle Microdoses (SP) use medium-potency P. galindoi on a 4-5-day dosing rhythm — built for creative flow and brainstorming. The Truffle Microdoses (OP) use the strongest species (P. tampanensis) on an alternating-day schedule for analytical focus and sustained cognitive sharpness.
History and Origin — Psilocybe mexicana, the Original Magic Truffle
Psilocybe mexicana has the longest human history of any psilocybin species. Mesoamerican cultures — particularly the Mazatec people of Oaxaca, Mexico — used this species in ceremonial and healing contexts for centuries before Western science became aware of it. In 1958, Swiss chemist Albert Hofmann (the same person who synthesised LSD) isolated psilocybin and psilocin from Psilocybe mexicana for the first time, making it the species that introduced these compounds to modern pharmacology.
The Fadiman Protocol itself comes from James Fadiman, a psychologist and researcher who has studied psychedelics since the 1960s. Fadiman published his microdosing protocol in The Psychedelic Explorer's Guide (2011), based on systematic self-reports collected from hundreds of volunteers. His 1-on-2-off schedule was deliberately conservative — designed to give people enough rest days to notice what changed, and to prevent the tolerance buildup that more frequent dosing can cause. It remains the most widely recommended starting protocol for first-time microdosers, and the pairing with P. mexicana — the mildest available species — makes biological sense: gentle compound, gentle schedule.
Effects — Truffle Microdoses (FP)
At a sub-perceptual 1 g fresh dose, Psilocybe mexicana does not produce hallucinations, uplifting, or perceptual distortion. The FP's character profile sits at the opposite end of the spectrum from the OP's cognitive sharpness — this is about emotional processing, not mental performance.
Psilocybin and psilocin bind to serotonin 5-HT2A receptors, primarily in the prefrontal cortex. At microdose levels, this serotonergic activity modulates the default-mode network — the brain circuitry associated with self-referential thinking, rumination, and habitual emotional patterns. A 2022 study in Neuropsychopharmacology showed that psilocybin promotes dendritic spine growth in cortical neurons, suggesting a structural basis for the increased mental flexibility and emotional openness users describe. These effects are cumulative — they build over weeks of consistent dosing, not after a single dose.
Based on Cibdol's character framework and customer feedback we've gathered at Azarius:
| Effect | Rating |
|---|---|
| Inner calm | 4/5 |
| Emotional stability | 4/5 |
| Mental flexibility | 3/5 |
| Mood lift | 3/5 |
| Creative flow | 2/5 |
| Analytical focus | 2/5 |
The pattern is the inverse of the OP: the FP leans toward emotion rather than cognition. The honest trade-off is that if you need creative output or analytical performance, this isn't the right protocol — you'll want the SP or OP for that. The FP deliberately sacrifices cognitive edge for emotional balance. If you're dealing with stress, processing a difficult period, or simply want a gentler baseline mood, that trade-off works in your favour.
The Global Drug Survey, the world's largest annual drug use survey, consistently reports that psilocybin ranks among the safest psychoactive substances in terms of emergency medical treatment — even at full doses. At microdose levels, the safety margin is significantly wider.
How to Use Truffle Microdoses (FP)
- Morning, empty stomach. Take your 1 g dose first thing. Wait at least 30 minutes before eating. An empty stomach allows the psilocybin prodrug to convert to psilocin more efficiently.
- Chew thoroughly. Break down the sclerotia tissue in your mouth — this speeds onset. P. mexicana has a soft, slightly crumbly texture that's easier to chew than the denser tampanensis. Swallow with water.
- Follow the 1-on-2-off schedule. Dose on Day 1. Observe on Day 2 — many people report a subtle "afterglow" where the calming effects linger. Rest on Day 3 to return to your baseline. Do not stack doses or double up after a missed day.
- Journal your observations. Pay attention to emotional responses, stress tolerance, sleep quality, and overall mood. The Fadiman Protocol is designed for self-observation — use it. After 2 weeks, review your entries for patterns.
- Cycle the protocol. Run the FP for 4-8 weeks, then take a 2-4 week break. This prevents tolerance buildup and gives you a clear picture of what changed versus your pre-protocol baseline.
- Store unused doses in the fridge. Keep between 2-8 °C. Fresh sclerotia are perishable — do not freeze, and use within the shelf date printed on the pack.
Taste and Texture — Truffle Microdoses (FP)
Psilocybe mexicana sclerotia are the mildest-tasting of the three Cibdol species. The flavour is earthy and nutty — similar to a raw cashew with a faint sour undertone — without the sharper tang of tampanensis or the slightly fermented edge of galindoi. The texture is softer and more crumbly than the other two species, which makes the 1 g dose quick to chew — about 10 seconds, then swallow. If you're sensitive to earthy flavours, wash it down with orange juice. At this dose size, masking the taste is barely necessary — it's a mouthful, not a meal.
Why Choose Truffle Microdoses (FP)?
- Mildest species of the three. Psilocybe mexicana is the gentlest truffle Cibdol offers — lower psilocybin concentration per gram than both galindoi (SP) and tampanensis (OP). If you're new to psilocybin, this is where you start.
- Most rest days in any protocol. The Fadiman schedule gives you 2 days off for every dose day. That means more time to observe effects, less exposure to the compound, and the lowest risk of tolerance buildup. No other standard protocol is this conservative.
- Pre-portioned accuracy. Each dose is exactly 1 g, vacuum-sealed by Cibdol. No scale needed, no variation between doses. Consistent dosing is the single biggest factor in reliable microdosing results — and this removes the guesswork entirely.
- Emotional integration, not performance. The FP is not a productivity hack. It targets inner calm, emotional stability, and mood balance — a different kind of support than the SP's creative flow or the OP's analytical edge. Good if you're going through a stressful period, or if you simply want a gentler daily experience without chasing cognitive performance.
- Longest-lasting pack. Six doses on a 1-on-2-off schedule last roughly 18 days — compared to 12 days on the OP and 8-9 days on the SP. More value per pack if you're trying microdosing for the first time and want to evaluate before committing to a faster protocol.
Safety and Harm Reduction — Truffle Microdoses (FP)
Psilocybin has a strong safety profile relative to other psychoactive substances. It is not physically addictive, carries very low physiological toxicity, and produces rapid tolerance that discourages compulsive redosing. The Global Drug Survey has ranked psilocybin-containing products among the least likely to require emergency medical attention across all categories surveyed.
Contraindications: Do not use psilocybin microdoses if you have a personal or family history of psychosis or schizophrenia. Psilocybin acts on serotonin pathways, and combining it with SSRIs (selective serotonin reuptake inhibitors) or MAO inhibitors can cause unpredictable interactions. If you are on any serotonergic medication, speak with your prescribing doctor before starting a microdosing protocol.
This is not a recreational product. At 1 g fresh, you will not feel "high." There are no visuals, no altered perception, no impairment. If for any reason you feel uneasy after a dose, remember: the effects of psilocybin are temporary. They pass within hours, and at microdose levels, within 1-2 hours at most. Stay hydrated, stay comfortable, and wait it out.
Do not combine with alcohol or other substances. Do not drive or operate heavy machinery until you know how your body responds to the protocol — though at this dose level, impairment is not expected.
Comparison — FP vs SP vs OP Microdosing Protocols
| Truffle Microdoses (FP) | Truffle Microdoses (SP) | Truffle Microdoses (OP) | |
|---|---|---|---|
| Species | Psilocybe mexicana | Psilocybe galindoi | Psilocybe tampanensis |
| Potency | Mild (gentlest) | Medium | Medium-strong (strongest) |
| Protocol | Fadiman Protocol | Stamets Protocol | One-Day Protocol |
| Schedule | 1 day on, 2 days off | 4-5 days on, 2-3 days off | 1 day on, 1 day off |
| Active days/week | 2-3 | 4-5 | 3-4 |
| Character | Relaxation, emotional integration, inner calm | Creative flow, divergent thinking, perspective shifts | Analytical focus, daily sharpness, work performance |
| Good for | First-time microdosers, people seeking calm and emotional balance, those processing stress or transitions | Designers, writers, musicians, anyone in creative problem-solving roles | Programmers, researchers, analysts, students with demanding cognitive workloads |
| Dose per portion | 1 g fresh | 1 g fresh | 1 g fresh |
| Portions | 6 | 6 | 6 |
Active Compound Profile — Psilocybe mexicana
Psilocybe mexicana sclerotia contain three principal tryptamine alkaloids:
| Compound | Role | Typical concentration (dry weight) |
|---|---|---|
| Psilocybin | Prodrug — converted to psilocin in the liver via dephosphorylation | 0.2-0.5% |
| Psilocin | Active metabolite — binds serotonin 5-HT2A receptors, responsible for cognitive and emotional effects | 0.01-0.1% |
| Baeocystine | Minor tryptamine alkaloid — similar structure to psilocybin, pharmacological contribution not fully characterised | Trace amounts |
Fresh sclerotia contain 65-70% water. A 1 g fresh dose yields approximately 0.3 g dry material, containing roughly 1-2 mg of psilocybin. At this level, psilocin concentrations in the brain remain below the threshold for perceptual changes, but are sufficient to engage 5-HT2A receptor-mediated neuroplasticity — including the dendritic spine growth documented in the 2022 Neuropsychopharmacology study and the default-mode network modulation observed in functional imaging research. The lower psilocybin concentration in P. mexicana compared to P. tampanensis (0.2-0.5% vs 0.3-0.7%) is what makes it the mildest option — less active compound per gram means a gentler experience at the same 1 g dose.
Norbaeocystine is present in trace amounts. Its pharmacological role remains under investigation, but like baeocystine it belongs to the tryptamine family and may contribute to the overall serotonergic profile of the sclerotia. The presence of multiple alkaloids — even in trace quantities — suggests a more varied interaction with serotonin receptors than purified psilocybin alone would produce.
Frequently Asked Questions
What is the Fadiman Protocol for microdosing?
The Fadiman Protocol is a microdosing schedule created by psychologist James Fadiman. You take one dose on Day 1, observe aftereffects on Day 2 (no dose), rest on Day 3, then repeat. It's the most conservative standard protocol — 2-3 active days per week — and the most recommended starting point for first-time microdosers.
What is in Cibdol Truffle Microdoses (FP)?
Each pack contains 6 individually portioned 1 g doses of fresh Psilocybe mexicana sclerotia (also called philosopher's stones or magic truffles). The active compounds are psilocybin, psilocin, and baeocystine — tryptamine alkaloids that act on serotonin receptors. At 1 g fresh, the dose is sub-perceptual.
Will I feel high from a 1 g microdose of Psilocybe mexicana?
No. One gram of fresh sclerotia contains approximately 1-2 mg of psilocybin — well below the perceptual threshold. You won't experience visuals, uplifting, or impairment. The effects are subtle and cumulative: reduced background stress, easier emotional processing, and a calmer baseline mood over weeks of consistent use.
Why is the FP recommended for beginners?
Two reasons: the mildest species and the most rest days. Psilocybe mexicana has the lowest psilocybin concentration of the three Cibdol species, and the Fadiman schedule gives you 2 off-days for every dose day. That combination means less exposure, more time to observe how your body responds, and the lowest chance of any unwanted effects.
How long does one pack last on the Fadiman Protocol?
Roughly 18 days. With 6 doses and a 3-day cycle (1 on, 2 off), each dose covers 3 calendar days. That's nearly three weeks from one pack — longer than the OP (12 days) or SP (8-9 days) on their respective schedules.
What is the difference between FP, SP, and OP microdosing truffles?
FP uses the mildest species (P. mexicana) on the most conservative schedule for emotional calm. SP uses mid-potency P. galindoi on a 4-5-day rhythm for creative flow. OP uses the strongest species (P. tampanensis) on alternating days for analytical focus. Choose based on what you need: calm, creativity, or cognition.
Can I take Truffle Microdoses (FP) with SSRIs?
Psilocybin and SSRIs both act on serotonin pathways. Most SSRI users report reduced or absent microdosing effects. Do not adjust your medication to microdose — speak with your prescribing doctor about any changes to your routine.
How should I store Truffle Microdoses (FP)?
Refrigerate at 2-8 °C. Keep the packaging sealed between uses. Fresh sclerotia are perishable — do not freeze, as this damages cell structure and degrades the active compounds. Use before the expiry date on the pack.
Is psilocybin microdosing safe?
Psilocybin has a strong safety profile: it is not addictive, carries very low physiological toxicity, and builds rapid tolerance that discourages overuse. The Global Drug Survey ranks psilocybin among the least likely substances to require emergency medical treatment. The main contraindications are a history of psychosis and concurrent use of serotonergic medications.
Last updated: April 2026
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Medische disclaimer. Deze inhoud is uitsluitend bedoeld ter informatie en vormt geen medisch advies. Raadpleeg een gekwalificeerde zorgverlener voordat je een stof gebruikt.










